Possible Treatment for LUFS

I have LUFS, which is Luteinized Unruptured Follicle Syndrome. With this condition, I have normal 28 cycles. I have normal BBT rises. I get a positive OPK. I even get a progesterone level over 15, at 7DPO. It all makes it look like I am normal. BUT I do not actually ovulate. My follicle does not pop.This is why the RE told me there was nothing wrong with me and IVF was the only way to go.
I came across this LUFS treatment Article on the internet. It was written two years ago by a DR.  in Japan. Here is my summary on it becuase the article is very complicated to read. Right before ovulation there is an increase in some type of white blood cells. This  reacts with  the follicle wall. It makes it thinner, so that when you get the LH surge it will pop open. This makes complete sense for me. I can grow a normal follicle on my own, but they never pop. THis medicine is supposed to increase your white blood cells to provide the missing reaction.
 I was very excited to have an option to pursue becuase it seems that everything else has failed. I emailed the Dr in Japan and he emailed me back the next day. He is still doing the research and now has a 90% success rate. I asked my Dr about it. He said that he never heard of it before. He is going to call the Dr in Japan and ask him about the research and then he will consider treating me with it....... I am so excited that I may finally have a real treatment after 3.5 years of infertility........
I am pasting the response from the Dr in Japan below...
__________________________________________________________________________________
     Thank you very much for your interest in my research!

     If your LUFS is not caused by severe adhesion of around ovaries due to endometriosis, pelvic surgeries, etc, the treatment using G-CSF is effective at the rate of more than 90 %.  The number of our clinical trial reached to 70 cycles and the effective rate is more than 90%.
We will publish the new paper in English regarding our clinical trial, when the numbers of the cycle reach to 100 cycles.

     G-CSF is widely used in the field of cancer treatment to increase the number of Granulocytes.  In the USA, it is marketed by Amgen with the brand name Neupogen (filgrastim), although we are using another type of G-CSF, lenograstim.  There are no differences between them.

     In our country, we can use any drug for any purpose, if patient gives her doctor an informed consent.
I don't know the situation in the USA.  If the situation is the same, you can receive G-CSF treatment by your doctor.
Until today, we have no side effects of G-CSF in our clinical trial.
If your doctor has more questions, I am willing to answer his questions.

     Thank you again for your interest!

     with best regards,

     Yours sincerely,



********************************************
Satoru Makinoda, M.D.
Professor and Chairman
Department of Obstetrics and Gynecology
Kanazawa Medical University
Uchinada
920-0293 Japan
E-mail:mak@kanazawa-med.ac.jp
Tel.:+81-76-218-8142
Fax.:+81-76-286-2629
********************************************

Sperm DNA Fragmentation Screening

Here is some information about sperm DNA fragmentation screening
from http://www.scsadiagnostics.com/

For trying-to-conceive (TTC) couples and their doctors, the SCSA test is the original and Gold Standard for sperm DNA fragmentation screening that delivers a highly accurate measure of male reproductive health. Because the SCSA analysis was pioneered, patented and tested for over 25 years by the founder and president of SCSA Diagnostics of Brookings, South Dakota, only SCSA Diagnostics can be trusted to provide accurate and time tested results. International medical literature states that SCSA is the ONLY sperm DNA fragmentation test that has an established clinically significant threshold to helping you determine sperm DNA health.

October 2010: The first month with no cysts!!!!!!!

 I discovered that the B6 the Dr put me on made my condition worse. B6 made me grow more follies and made them large and stick around. I started to get a traffic jam in there and the cysts were staying from one cycle to the next. I went off the B6 and things returned to normal. Well normal for me.

Oct 2010: No TEBB thanks to Biaxin Yeah CD3 NO CYSTS  for the first time. YEAH Thanks to the PIO shot. So I guess the agonizing pain was worth it. The weird thing on my right ovary is still there.......CD13, follie on the left is getting close to 20mm. Took the ovidrel and menopur triggers on CD15. CD18 us showed the follie was still there and it was 23mm. My Peak+7 BW was great P20 and E193
I took the PIO shots on P+3, 5, 7,9 without any problems. I found a great cartoon butt to show my husband where to inject. He did great and I had no pain.

A New Article About the Gianna Center from Faith and Family

Here is a new article about the Gianna Center
Faith and Family Article About the Gianna Center

September 2010

Sept 2010: No TEBB. thanks to Biaxin Yeah! CD 3, some big cysts were still there. =( CD 15, us showed a nice follie in the middle of the cysts. The Dr told me to trigger. I was surprised. I added menopur to the ovidrel in the hopes that the extra LH in the menopur would help. CD18, us showed follicle collapsing, but unsure of what that means. He had me take a PIO shot the night before, so maybe that affected things.  Blood work was P: 31.9 and E 521  The nurse saw something solid on my right ovary and did not know what it was. UGH.....

PIO shots

In September, my dr ordered an Intramuscular PIO shot for the first time. My husband gave it to me and injected me in the wrong spot. He got too close to my sciatic nerve. I had severe leg pain and I could barely walk. It was a deep muscle/ligament pain that stopped my leg from functioning. It was not just a sore muscle ache.  I was limping for two weeks. I could not cross my legs, I could not get into the car without crying, it hurt so bad to swing my leg over. I want to warn you, if you are going to take these shots, to make sure that you get the right spot.So here is a great picture of a cartoon butt, that shows the correct spots. This is for medical/educational purposes.

Gianna Center Special, 2 WEEKS ONLY:

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Book your appointment online now at: http://gianna-medicine.genbook.com
*Date of the appointment must fall between 9/7 and 9/17 to qualify for the special promotion.